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Breakthrough

The Quest for Life-Changing Medicines

Published by Oneworld Publications
Distributed by Simon & Schuster

About The Book

Meet the doctors, scientists, patients and campaigners tackling the world’s worst diseases

We often hear about the dark side of the pharmaceutical industry – from extortionate pricing to the opioid epidemic. But there’s another story to be told.

Through the story of eight revolutionary treatments, Dr William Pao cuts to the innovative heart of medical science and celebrates the tireless work of those fighting for better care. Behind each of these medicines – whether a potentially life-saving new treatment for cancer, or something as commonplace as paracetamol – there stands a cast of characters and a wealth of stories.

The trajectory from the laboratory to the local chemist is rarely a straight line. Eureka moments are few are far between. Drug hunting demands leaps of imagination and lateral thinking, the accumulation of the knowledge and expertise of many, and – nearly always – a hefty dollop of luck.

Breakthrough documents these journeys and grants a privileged look at the stories behind the medicines that improve – and very often save – our lives.

About The Author

Dr. William Pao is a physician-scientist whose career has spanned academia and industry. He was previously Chief Development Officer for Pfizer, and prior to that, Head of the Roche Pharma Research & Early Development unit, where he oversaw the discovery and early development of a portfolio of new molecular entities to treat a range of diseases, from cancer to rare blood disorders.

Before joining industry, William was Professor of Medicine at Vanderbilt University in Nashville, where he held the Cornelius Abernathy Craig Chair in Medical and Surgical Oncology. Internationally recognized for his ground-breaking work in translational medicine and for his leadership in cancer genomics and personalized medicine, William is also the co-founder of MyCancerGenome, an indispensable online tool designed to enable a genetically informed approach to cancer medicine.

Product Details

  • Publisher: Oneworld Publications (October 3, 2024)
  • Length: 352 pages
  • ISBN13: 9780861547357

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Raves and Reviews

This book is a must read for anyone interested in learning how new therapeutics are created and should also appeal to the curious reader fascinated by innovation, popular science, biology and medicine.’ —Siddhartha Mukherjee, author of the Pulitzer Prize winner The Emperor of All Maladies

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